Human serine/threonine/tyrosine interacting-like 1 ELISA Kit | STYXL1 elisa kit
Human Serine/threonine/tyrosine-interacting-like protein 1, STYXL1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
STYXL1: a pseudophosphatase of the dual specificity phosphatase sub-family of the protein tyrosine phosphatases. Contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphoprotein phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Interacts with G3BP-1, an RNA-binding protein with endoribonuclease activity that is recruited to stress granules (SGs) during stress. SGs are involved in mRNA sorting in the storing of untranslated mRNAs. STYXL1 inhibits G3BP-induced stress granule formation. Five isoforms of the human protein are produced by alternative splicing.
Protein type: Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q11.23
Molecular Function: protein tyrosine/serine/threonine phosphatase activity
Biological Process: protein amino acid dephosphorylation