Human sperm associated antigen 4 ELISA Kit | SPAG4 elisa kit

Human Sperm-associated antigen 4 protein, SPAG4 ELISA Kit

Cat. Num. AAA9327855

• Gene Names: SPAG4; SUN4; CT127
• Reactivity: Human
• Synonyms: sperm associated antigen 4; Human Sperm-associated antigen 4 protein; SPAG4 ELISA Kit; Human Sperm-associated antigen 4 protein (SPAG4) ELISA kit; RP1-309K20.4; acrosomal protein ACR55; outer dense fiber-associated protein SPAG4; sperm tail protein; SPAG4 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
• Assay Type: Sandwich (Quantitative)
• Detection Range: 0.625ng/ml-20ng/ml.
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SPAG4 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SPAG4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 11037055
• NCBI GeneID: 6676
• NCBI Accession #: NP_003107.1
• NCBI GenBank Nucleotide #: NM_003116.1
• UniProt Accession #: Q9NPE6; O43648
• Molecular Weight: 48,165 Da
• NCBI Official Full Name: sperm-associated antigen 4 protein
• NCBI Official Synonym Full Names: sperm associated antigen 4
• NCBI Official Symbol: SPAG4
• NCBI Official Synonym Symbols: SUN4; CT127
• NCBI Protein Information: sperm-associated antigen 4 protein; sperm tail protein; acrosomal protein ACR55; cancer/testis antigen 127; SUN domain-containing protein 4; Sad1 and UNC84 domain containing 4; outer dense fiber-associated protein SPAG4
• UniProt Protein Name: Sperm-associated antigen 4 protein
• Protein Family: Sperm-associated antigen 4 protein
• UniProt Gene Name: SPAG4
• UniProt Synonym Gene Names: SUN4
• UniProt Entry Name: SPAG4_HUMAN

NCBI Description

The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development. [provided by RefSeq, Jul 2008]

Uniprot Description

SPAG4: May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail.

Protein type: Membrane protein, integral; Cancer Testis Antigen (CTA); Microtubule-binding; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: cytoskeleton; cytoplasm; integral to membrane; nuclear envelope

Molecular Function: structural molecule activity

Biological Process: spermatogenesis; nuclear membrane organization and biogenesis