Rat SUMO1/sentrin/SMT3 specific peptidase 2 ELISA Kit | SENP2 elisa kit
Rat Sentrin-specific protease 2, SENP2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds the GSK-3beta interacting protein Axin; inhibits the Wnt signalling pathway via inhibition of Axin protein complex formation [RGD, Feb 2006]
Uniprot Description
SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Belongs to the peptidase C48 family.
Protein type: EC 3.4.22.68; Protease
Cellular Component: nuclear body; PML body; nuclear membrane; cytoplasmic membrane-bound vesicle; cytoplasm; nuclear pore; cytoplasmic vesicle; nucleus
Molecular Function: protein domain specific binding; SUMO-specific protease activity
Biological Process: protein desumoylation; negative regulation of DNA damage response, signal transduction by p53 class mediator; regulation of DNA endoreduplication; protein transport; mRNA transport; Wnt receptor signaling pathway; heart development; regulation of protein metabolic process; positive regulation of transcription from RNA polymerase II promoter; dorsal/ventral axis specification; positive regulation of protein amino acid phosphorylation; proteolysis; negative regulation of protein binding
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Product Notes
The Rat SENP2 senp2 (Catalog #AAA9325997) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325997 ELISA Kit recognizes Rat SENP2. It is sometimes possible for the material contained within the vial of "SUMO1/sentrin/SMT3 specific peptidase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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