Human NTF2-like export factor 1 ELISA Kit | NXT1 elisa kit
Human NTF2-related export protein 1, NXT1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
NXT1: Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 20p12-p11.2
Cellular Component: cytoplasm; nuclear pore; nuclear speck
Molecular Function: protein binding; Ran GTPase binding
Biological Process: RNA export from nucleus; protein export from nucleus
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Product Notes
The Human NXT1 nxt1 (Catalog #AAA9323302) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323302 ELISA Kit recognizes Human NXT1. It is sometimes possible for the material contained within the vial of "NTF2-like export factor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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