Mouse dual specificity phosphatase 10 ELISA Kit | DUSP10 elisa kit

Mouse Dual specificity protein phosphatase 10, DUSP10 ELISA Kit

Cat. Num. AAA9323287

• Gene Names: Dusp10; MKP5; MKP-5; AI158871; 2610306G15Rik
• Reactivity: Mouse
• Synonyms: dual specificity phosphatase 10; Mouse Dual specificity protein phosphatase 10; DUSP10 ELISA Kit; Mouse Dual specificity protein phosphatase 10 (DUSP10) ELISA kit; MKP-5; MKP5; dual specificity phosphatase MKP-5; map kinase phosphatase 5; serine/threonine specific protein phosphatase; DUSP10 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 0.5 ng/ml - 16 ng/ml
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for DUSP10 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of DUSP10 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 31560303
• NCBI GeneID: 63953
• NCBI Accession #: NP_071302.2
• NCBI GenBank Nucleotide #: NM_022019.5
• UniProt Accession #: Q9ESS0; Q8R3L3; Q9CZY9
• Molecular Weight: 52,532 Da
• NCBI Official Full Name: dual specificity protein phosphatase 10
• NCBI Official Synonym Full Names: dual specificity phosphatase 10
• NCBI Official Symbol: Dusp10
• NCBI Official Synonym Symbols: MKP5; MKP-5; AI158871; 2610306G15Rik
• NCBI Protein Information: dual specificity protein phosphatase 10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5
• UniProt Protein Name: Dual specificity protein phosphatase 10
• Protein Family: Dual specificity protein phosphatase
• UniProt Gene Name: Dusp10
• UniProt Synonym Gene Names: Mkp5; MAP kinase phosphatase 5; MKP-5
• UniProt Entry Name: DUS10_MOUSE

Uniprot Description

MKP-5: a non-receptor, dual-specificity phosphoprotein phosphatase (DUSP). Different members of the DUSP family show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. Contains 1 rhodanese domain.

Protein type: EC 3.1.3.16; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.48

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleus

Molecular Function: MAP kinase phosphatase activity; hydrolase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: negative regulation of oligodendrocyte differentiation; negative regulation of JNK activity; negative regulation of JNK cascade; regulation of adaptive immune response; dephosphorylation; oligodendrocyte differentiation; response to lipopolysaccharide; protein amino acid dephosphorylation; negative regulation of stress-activated MAPK cascade; inactivation of MAPK activity; regulation of innate immune response