Western Blot (WB)
(Western blotting analysis of Hsp90 alpha and beta protein by antibody MBH90AB to both Hsp90 alpha and beta isoform.)
Mouse HSP90 alpha/beta Antibody
Anti-HSP90 alpha/beta Purified
Reactivity
Cow, Mouse, Human
Applications
Western Blot
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
HSP90 alpha/beta; Anti-HSP90 alpha/beta Purified; HSP90A; HSP90B; LAP-2; LAP2; EL52; anti-HSP90 alpha/beta antibody
Host
Mouse
Reactivity
Cow, Mouse, Human
Isotype
IgG1
Clone Number
MBH90AB
Specificity
The antibody MBH90AB recognizes the epitope EEEVE within N-terminal part of ubiquitously expressed Hsp90 alpha and Hsp90 beta intracellular proteins with calculated Mw of 84.7 kDa and 83.3 kDa, respectively, however, migrating as 90 kDa bands under reducing SDS-PAGE conditions.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-HSP90 alpha/beta antibody
Western Blot (WB)
Immunogen
Peptide corresponding to the sequence EEVHHGEEEVEC within N-terminal part of human Hsp90.
Preparation and Storage
Store at 2-8 degree C.
Western Blot (WB)
(Western blotting analysis of Hsp90 alpha and beta protein by antibody MBH90AB to both Hsp90 alpha and beta isoform.)
Western Blot (WB)
(Western blotting analysis of Hsp90 alpha and beta protein by antibody MBH90AB to both Hsp90 alpha and beta isoform.)
Related Product Information for anti-HSP90 alpha/beta antibody
Hsp90 (heat shock protein 90) is one of the most abundant chaperones in the cytosol of eukaryotic cells. It interacts with various proteins, including protein kinases and transcription factors, and either facilitates their stabilization and activation or directs them for proteasomal degradation. Hsp90 thus affects multiple signaling pathways and biological processes and modulation of this single target offers the prospect of simultaneous intervence to various key points of oncogenic transformation. Hsp90 operates as a dimer in a conformational cycle driven by ATP binding and hydrolysis. There are two isoforms, alpha and beta, of vertebrate Hsp90. Whereas Hsp90 beta is expressed constitutively to a high level, Hsp90 alpha is stress-inducible and is overexpressed in many cancerous cells.
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Product Notes
The HSP90 alpha/beta (Catalog #AAA1800959) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-HSP90 alpha/beta Purified reacts with Cow, Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSP90 alpha/beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the HSP90 alpha/beta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSP90 alpha/beta, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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