Human transcription elongation factor B polypeptide 3B (elongin A2) ELISA Kit | TCEB3B elisa kit
Human RNA polymerase II transcription factor SIII subunit A2, TCEB3B ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
TCEB3B: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 18q21.1
Cellular Component: integral to membrane; nucleus
Molecular Function: DNA binding
Biological Process: transcription from RNA polymerase II promoter; regulation of RNA elongation
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Product Notes
The Human TCEB3B tceb3b (Catalog #AAA9322922) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322922 ELISA Kit recognizes Human TCEB3B. It is sometimes possible for the material contained within the vial of "transcription elongation factor B polypeptide 3B (elongin A2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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