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Western Blot (WB) (Western Blot analysis of extracts of various cells, using TCEB3B antibody.)

Rabbit anti-Mouse, Rat TCEB3B Polyclonal Antibody | anti-TCEB3B antibody

TCEB3B Polyclonal Antibody

Gene Names
ELOA2; HsT832; TCEB3B; TCEB3L
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
TCEB3B; Polyclonal Antibody; TCEB3B Polyclonal Antibody; Elongin-A2; Elongin A2; EloA2; Transcription elongation factor B polypeptide 3B; TCEB3L; anti-TCEB3B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TCEB3B polyclonal antibody detects endogenous levels of TCEB3B protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
753
Applicable Applications for anti-TCEB3B antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human TCEB3B.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cells, using TCEB3B antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cells, using TCEB3B antibody.)
Related Product Information for anti-TCEB3B antibody
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 100kDa
NCBI Official Full Name
elongin-A2
NCBI Official Synonym Full Names
elongin A2
NCBI Official Symbol
ELOA2
NCBI Official Synonym Symbols
HsT832; TCEB3B; TCEB3L
NCBI Protein Information
elongin-A2
UniProt Protein Name
RNA polymerase II transcription factor SIII subunit A2
UniProt Gene Name
TCEB3B
UniProt Synonym Gene Names
TCEB3L; EloA2
UniProt Entry Name
ELOA2_HUMAN

NCBI Description

This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

TCEB3B: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: integral to membrane; nucleus

Molecular Function: DNA binding

Biological Process: transcription from RNA polymerase II promoter; regulation of RNA elongation

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Product Notes

The TCEB3B tceb3b (Catalog #AAA3009222) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TCEB3B Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TCEB3B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TCEB3B tceb3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCEB3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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