Human GDNF family receptor alpha 3 ELISA Kit | GFRA3 elisa kit
Human GDNF family receptor alpha-3, GFRA3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]
Uniprot Description
GFRA3: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. Belongs to the GDNFR family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 5q31.1-q31.3
Cellular Component: extrinsic to membrane; intracellular membrane-bound organelle; cytoplasm; plasma membrane; external side of plasma membrane
Molecular Function: axon guidance receptor activity; receptor binding
Biological Process: axon guidance; nervous system development; sympathetic nervous system development; neuron migration; signal transduction; peripheral nervous system development
Research Articles on GFRA3
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Product Notes
The Human GFRA3 gfra3 (Catalog #AAA9318775) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318775 ELISA Kit recognizes Human GFRA3. It is sometimes possible for the material contained within the vial of "GDNF family receptor alpha 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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