Rat SH3 and multiple ankyrin repeat domains 1 ELISA Kit | SHANK1 elisa kit
Rat SH3 and multiple ankyrin repeat domains protein 1, SHANK1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
a scaffold protein in the post synaptic density that forms a complex with GKAP and PSD-95 [RGD, Feb 2006]
Uniprot Description
SHANK1: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Belongs to the SHANK family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Cellular Component: postsynaptic membrane; neuron projection; membrane; dendrite; cytoplasm; dendritic spine; plasma membrane; ionotropic glutamate receptor complex; excitatory synapse; synapse; intracellular; cell junction; N-methyl-D-aspartate selective glutamate receptor complex
Molecular Function: protein C-terminus binding; somatostatin receptor binding; ionotropic glutamate receptor binding; identical protein binding; protein binding; receptor signaling complex scaffold activity; protein complex binding; GKAP/Homer scaffold activity; SH3 domain binding
Biological Process: synapse maturation; negative regulation of actin filament bundle formation; olfactory behavior; righting reflex; cytoskeletal anchoring; social behavior; habituation; determination of affect; long-term memory; adult behavior; protein complex assembly; neuromuscular process controlling balance; associative learning
Research Articles on SHANK1
Similar Products
Product Notes
The Rat SHANK1 shank1 (Catalog #AAA9317988) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317988 ELISA Kit recognizes Rat SHANK1. It is sometimes possible for the material contained within the vial of "SH3 and multiple ankyrin repeat domains 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
