Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H ELISA Kit | APOBEC3H elisa kit
Human DNA dC->dU-editing enzyme APOBEC-3H, APOBEC3H ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Uniprot Description
APOBEC3H: DNA cytidine deaminase which may provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.5.4.-; Hydrolase
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; zinc ion binding; cytidine deaminase activity
Biological Process: negative regulation of retroviral genome replication; innate immune response; cytidine deamination; negative regulation of viral reproduction; defense response to virus
Research Articles on APOBEC3H
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Product Notes
The Human APOBEC3H apobec3h (Catalog #AAA9317543) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317543 ELISA Kit recognizes Human APOBEC3H. It is sometimes possible for the material contained within the vial of "apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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