Rat thioredoxin reductase 2 ELISA Kit | TXNRD2 elisa kit
Rat Thioredoxin reductase 2, mitochondrial, TXNRD2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene product belongs to the family of pyridine nucleotide-disulfide oxidoreductases. It is a mitochondrial enzyme that catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. This protein contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Uniprot Description
TXNRD2: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; Mitochondrial; EC 1.8.1.9; Nuclear receptor co-regulator; Nucleotide Metabolism - pyrimidine
Cellular Component: cell soma; mitochondrion; axon; dendrite; cytoplasm
Molecular Function: protein dimerization activity; protein homodimerization activity; mercury (II) reductase activity; thioredoxin-disulfide reductase activity; FAD binding; mercury ion binding; NADP binding
Biological Process: response to drug; response to selenium ion; response to hyperoxia; response to oxygen radical; response to hydrogen peroxide; cell redox homeostasis; heart development; detoxification of mercury ion; hemopoiesis
Research Articles on TXNRD2
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Product Notes
The Rat TXNRD2 txnrd2 (Catalog #AAA9317275) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317275 ELISA Kit recognizes Rat TXNRD2. It is sometimes possible for the material contained within the vial of "thioredoxin reductase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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