Human phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2 ELISA Kit | PREX2 elisa kit
Human Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein, PREX2 ELISA Kit
Gene Names
PREX2; DEP.2; DEPDC2; P-REX2; PPP1R129; 6230420N16Rik
Reactivity
Human
Synonyms
phosphatidylinositol-3; 4; 5-trisphosphate-dependent Rac exchange factor 2; Human Phosphatidylinositol 3; 5-trisphosphate-dependent Rac exchanger 2 protein; PREX2 ELISA Kit; 5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) ELISA kit; DEP.2; DEPDC2; P-REX2; 6230420N16Rik; DEP domain containing 2; PtdIns (3; 5) -dependent Rac exchanger 2; phosphatidylinositol 3; 5-trisphosphate-dependent RAC exchanger 2; PREX2 elisa kit
Reactivity
Human
Assay Type
Quantitative Sandwich
Detection Range
0.25ng/ml-8ng/ml
Sensitivity
0.1ng/ml
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for PREX2 elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of PREX2 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
182,622 Da
NCBI Official Full Name
phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform a
NCBI Official Synonym Full Names
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
NCBI Official Symbol
PREX2
NCBI Official Synonym Symbols
DEP.2; DEPDC2; P-REX2; PPP1R129; 6230420N16Rik
NCBI Protein Information
phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; DEP domain-containing protein 2; PtdIns(3,4,5)-dependent Rac exchanger 2; protein phosphatase 1, regulatory subunit 129
UniProt Protein Name
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
UniProt Gene Name
PREX2
UniProt Synonym Gene Names
DEPDC2; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2
UniProt Entry Name
PREX2_HUMAN
Uniprot Description
PREX2: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs, Rac/Rho; GEFs; Phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 8q13.2
Cellular Component: plasma membrane
Molecular Function: Rac guanyl-nucleotide exchange factor activity
Biological Process: G-protein coupled receptor protein signaling pathway; phosphoinositide 3-kinase cascade; adult locomotory behavior; dendrite morphogenesis
Research Articles on PREX2
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Product Notes
The Human PREX2 prex2 (Catalog #AAA9317181) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317181 ELISA Kit recognizes Human PREX2. It is sometimes possible for the material contained within the vial of "phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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