Mouse thioredoxin domain containing 3 (spermatozoa) ELISA Kit | TXNDC3 elisa kit
Mouse Thioredoxin domain-containing protein 3, TXNDC3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TXNDC3: Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds. Defects in NME8 are the cause of primary ciliary dyskinesia type 6 (CILD6). CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
Protein type: Oxidoreductase; Kinase, nucleoside diphosphate; Other group; NDK family
Cellular Component: cytoplasm; intracellular
Molecular Function: nucleoside diphosphate kinase activity; ATP binding
Biological Process: GTP biosynthetic process; CTP biosynthetic process; cell redox homeostasis; UTP biosynthetic process; multicellular organismal development; nucleoside diphosphate phosphorylation; spermatogenesis; cell differentiation
Research Articles on TXNDC3
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Product Notes
The Mouse TXNDC3 nme8 (Catalog #AAA9316884) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316884 ELISA Kit recognizes Mouse TXNDC3. It is sometimes possible for the material contained within the vial of "thioredoxin domain containing 3 (spermatozoa), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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