Human regulatory factor X, 4 (influences HLA class II expression) ELISA Kit | RFX4 elisa kit

Human Transcription factor RFX4, RFX4 ELISA Kit

Cat. Num. AAA9316594

• Gene Names: RFX4; NYD-SP10
• Reactivity: Human
• Synonyms: regulatory factor X; 4 (influences HLA class II expression); Human Transcription factor RFX4; RFX4 ELISA Kit; Human Transcription factor RFX4 (RFX4) ELISA kit; NYD-SP10; regulatory factor X4; isoform c; transcription factor NYD-sp10; RFX4 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 331999966
• NCBI GeneID: 5992
• NCBI Accession #: NP_001193620.1
• NCBI GenBank Nucleotide #: NM_001206691.1
• UniProt Accession #: Q33E94; Q33DW6; Q33DW7; Q33E95; Q6YM53; Q8MHQ1; Q8NC78; Q8NDF9; Q8SNA1; Q96S80; A8K5Y0; B2RDW4
• Molecular Weight: 83,368 Da
• NCBI Official Full Name: transcription factor RFX4 isoform d
• NCBI Official Synonym Full Names: regulatory factor X, 4 (influences HLA class II expression)
• NCBI Official Symbol: RFX4
• NCBI Official Synonym Symbols: NYD-SP10
• NCBI Protein Information: transcription factor RFX4; testis development protein NYD-SP10; winged-helix transcription factor RFX4
• UniProt Protein Name: Transcription factor RFX4
• Protein Family: Transcription factor
• UniProt Gene Name: RFX4
• UniProt Entry Name: RFX4_HUMAN

NCBI Description

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

Uniprot Description

RFX4: May activate transcription by interacting directly with the X-box. Belongs to the RFX family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: nucleus

Molecular Function: protein binding; chromatin binding; transcription factor activity

Biological Process: dorsal spinal cord development; regulation of transcription from RNA polymerase II promoter; telencephalon development; transcription, DNA-dependent; cerebellar cortex morphogenesis; midbrain development; cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of smoothened signaling pathway in ventral spinal cord patterning