Typical Testing Data/Standard Curve (for reference only)
Rat gamma-glutamyltransferase 1 ELISA Kit | GGT1 elisa kit
Rat Gamma-glutamyltranspeptidase 1, GGT1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
required in the glutathione metabolism [RGD, Feb 2006]
Uniprot Description
GGT1: Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive. Defects in GGT1 are a cause of glutathionuria (GLUTH); also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease. Belongs to the gamma-glutamyltransferase family. 3 isoforms of the human protein are produced by alternative promoter.
Protein type: Membrane protein, integral; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; Transferase; EC 3.4.19.14; EC 3.4.19.13; EC 2.3.2.2; Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - selenoamino acid; Other Amino Acids Metabolism - glutathione
Cellular Component: extracellular space; integral to plasma membrane; plasma membrane
Molecular Function: gamma-glutamyltransferase activity
Biological Process: peptide modification; glutamate metabolic process; regulation of immune system process; cysteine biosynthetic process; response to lipopolysaccharide; proteolysis; response to estradiol stimulus; leukotriene biosynthetic process; regulation of inflammatory response; glutathione catabolic process; glutathione biosynthetic process; spermatogenesis; zymogen activation; aging
Research Articles on GGT1
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Product Notes
The Rat GGT1 ggt1 (Catalog #AAA923419) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA923419 ELISA Kit recognizes Rat GGT1. It is sometimes possible for the material contained within the vial of "gamma-glutamyltransferase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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