SPCS1 blocking peptide

SPCS1 Blocking Peptide (Center)

Gene Names

SPCS1; SPC1; SPC12; HSPC033; YJR010C-A

Synonyms

SPCS1; SPCS1 Blocking Peptide (Center); Signal peptidase complex subunit 1; 34--; Microsomal signal peptidase 12 kDa subunit; SPase 12 kDa subunit; SPC12; SPCS1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 86-100 of HUMAN SPCS1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

102

Cellular Location

Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SPCS1 blocking peptide

Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

NCBI and Uniprot Product Information

NCBI GI #

557952606

NCBI GeneID

28972

UniProt Accession #

Q9Y6A9; Q9BVW1; B3KNF8

Molecular Weight

11,805 Da

NCBI Official Full Name

Signal peptidase complex subunit 1

NCBI Official Synonym Full Names

signal peptidase complex subunit 1

NCBI Official Symbol

SPCS1

NCBI Official Synonym Symbols

SPC1; SPC12; HSPC033; YJR010C-A

NCBI Protein Information

signal peptidase complex subunit 1

UniProt Protein Name

Signal peptidase complex subunit 1

Protein Family

Signal peptidase complex

UniProt Gene Name

SPCS1

UniProt Synonym Gene Names

SPC12; SPase 12 kDa subunit

UniProt Entry Name

SPCS1_HUMAN

Uniprot Description

SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.

Protein type: Endoplasmic reticulum; Amino Acid Metabolism - lysine degradation; Membrane protein, integral; Membrane protein, multi-pass; Protease; Cofactor and Vitamin Metabolism - biotin; EC 3.4.-.-

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex

Molecular Function: protein binding

Biological Process: protein targeting to ER; proteolysis; signal peptide processing

Research Articles on SPCS1

1. cis-acting regulatory polymorphisms acting on GNL3 and SPCS1 contribute to the OA association signal at chromosome 3p21, and these genes therefore merit further investigation.

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Product Notes

The SPCS1 spcs1 (Catalog #AAA9230223) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SPCS1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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SPCS1 blocking peptide