Lhx1 blocking peptide

Mouse Lhx1 Blocking Peptide (C-term)

• Gene Names: Lhx1; Lim1
• Synonyms: Lhx1; Mouse Lhx1 Blocking Peptide (C-term); LIM/homeobox protein Lhx1; LIM homeobox protein 1; Homeobox protein Lim-1; Lim-1; Lim1; Lhx1 blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 332-345 of HUMAN Lhx1
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 406

• Cellular Location: Nucleus
• Tissue Location: In mid to late stage embryos, expressed in a restricted region of mesoderm in the primitive streak. At 7.5 days, expressed in a horseshoe shape at the periphery of the node, as well as along both sides of the adjacent notochord. Also present in presumptive lateral and intermediate mesoderm. Later, expression become progressively restricted to intermediate mesoderm, and the developing excretory system including the pronephric region, mesonephros, nephric duct and metanephros. In the metanephros, strongly expressed in renal vesicles and S-shaped and coma-shaped bodies, as well as in the ureteric bud and its derivatives. Also expressed in the dorsal root ganglia. By stage 10.5, also expressed in regions of the central nervous system in the telencephalon through to the spinal cord. In adults, expressed in the cerebellum/medulla and kidney, and at very low levels in the cerebrum.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for Lhx1 blocking peptide

Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

NCBI and Uniprot Product Information

• NCBI GI #: 51702763
• NCBI GeneID: 16869
• UniProt Accession #: P63006; P36199
• Molecular Weight: 44,780 Da
• NCBI Official Full Name: LIM/homeobox protein Lhx1
• NCBI Official Synonym Full Names: LIM homeobox protein 1
• NCBI Official Symbol: Lhx1
• NCBI Official Synonym Symbols: Lim1
• NCBI Protein Information: LIM/homeobox protein Lhx1
• UniProt Protein Name: LIM/homeobox protein Lhx1
• UniProt Gene Name: Lhx1
• UniProt Synonym Gene Names: Lim-1; Lim1; LIM homeobox protein 1
• UniProt Entry Name: LHX1_MOUSE

Uniprot Description

LHX1: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

Protein type: Transcription factor; Cell development/differentiation

Cellular Component: intracellular; nucleus; protein complex

Molecular Function: protein binding; transcription factor activity

Biological Process: anatomical structure formation; anatomical structure morphogenesis; anterior/posterior axis specification; anterior/posterior pattern formation; cell-cell signaling; cerebellar Purkinje cell differentiation; cerebellum development; cervix development; dorsal/ventral pattern formation; ectoderm formation; embryonic pattern specification; embryonic retina morphogenesis in camera-type eye; embryonic viscerocranium morphogenesis; endoderm formation; fallopian tube development; forebrain regionalization; gastrulation with mouth forming second; kidney development; motor axon guidance; negative regulation of transcription, DNA-dependent; pattern specification process; positive regulation of embryonic development; positive regulation of transcription, DNA-dependent; post-embryonic development; Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; regulation of gene expression; somite rostral/caudal axis specification; spinal cord association neuron differentiation; transcription from RNA polymerase II promoter; ureteric bud development; urogenital system development; uterus development; vagina development