LONP2 blocking peptide

LONP2 Antibody (N-term) Blocking Peptide

• Gene Names: LONP2; LONP; LONPL
• Synonyms: LONP2; LONP2 Antibody (N-term) Blocking Peptide; Lon protease homolog 2; peroxisomal; 3421-; Lon protease-like protein 2; Lon protease 2; Peroxisomal Lon protease; LONP; LONP2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 852

• Cellular Location: Peroxisome matrix
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for LONP2 blocking peptide

ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.

NCBI and Uniprot Product Information

• NCBI GI #: 74727668
• NCBI GeneID: 83752
• UniProt Accession #: Q86WA8; Q0D2H6; Q8N3B9; Q8NCE9; Q96K43; B7ZKL7
• Molecular Weight: 89,660 Da
• NCBI Official Full Name: Lon protease homolog 2, peroxisomal
• NCBI Official Synonym Full Names: lon peptidase 2, peroxisomal
• NCBI Official Symbol: LONP2
• NCBI Official Synonym Symbols: LONP; LONPL
• NCBI Protein Information: lon protease homolog 2, peroxisomal
• UniProt Protein Name: Lon protease homolog 2, peroxisomal
• UniProt Gene Name: LONP2
• UniProt Synonym Gene Names: Lon protease 2
• UniProt Entry Name: LONP2_HUMAN

Uniprot Description

LONP2: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1. Belongs to the peptidase S16 family.

Protein type: Protease; EC 3.4.21.-

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: membrane; peroxisomal matrix; peroxisome

Molecular Function: ATP-dependent peptidase activity; enzyme binding; peptidase activity; protease binding; protein binding; receptor binding

Biological Process: misfolded or incompletely synthesized protein catabolic process; protein processing; protein targeting to peroxisome; regulation of fatty acid beta-oxidation