JAKMIP1 blocking peptide
JAKMIP1 Antibody (Center) Blocking Peptide
Gene Names
JAKMIP1; JAMIP1; MARLIN1; Gababrbp
Synonyms
JAKMIP1; JAKMIP1 Antibody (Center) Blocking Peptide; Janus kinase and microtubule-interacting protein 1; GABA-B receptor-binding protein; Multiple alpha-helices and RNA-linker protein 1; Marlin-1; GABABRBP; JAMIP1; MARLIN1; JAKMIP1 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human JAKMIP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
626
Cellular Location
Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note: Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells
Tissue Location
Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for JAKMIP1 blocking peptide
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
53,973 Da
NCBI Official Full Name
Janus kinase and microtubule-interacting protein 1
NCBI Official Synonym Full Names
janus kinase and microtubule interacting protein 1
NCBI Official Symbol
JAKMIP1
NCBI Official Synonym Symbols
JAMIP1; MARLIN1; Gababrbp
NCBI Protein Information
janus kinase and microtubule-interacting protein 1
UniProt Protein Name
Janus kinase and microtubule-interacting protein 1
Protein Family
UniProt Gene Name
JAKMIP1
UniProt Synonym Gene Names
GABABRBP; JAMIP1; MARLIN1; Marlin-1
UniProt Entry Name
JKIP1_HUMAN
Uniprot Description
JAKMIP1: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. Belongs to the JAKMIP family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 4p16.1
Cellular Component: extrinsic to membrane; ribonucleoprotein complex
Molecular Function: GABA receptor binding; protein binding; RNA binding
Biological Process: cognition
Research Articles on JAKMIP1
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Product Notes
The JAKMIP1 jakmip1 (Catalog #AAA9227787) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "JAKMIP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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