MFAP5 blocking peptide

MFAP5 Antibody (C-term) Blocking Peptide

• Gene Names: MFAP5; AAT9; MP25; MAGP2; MAGP-2; MFAP-5
• Synonyms: MFAP5; MFAP5 Antibody (C-term) Blocking Peptide; Microfibrillar-associated protein 5; MFAP-5; MP25; Microfibril-associated glycoprotein 2; MAGP-2; MAGP2; MFAP5 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human MFAP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 173

• Cellular Location: Secreted, extracellular space, extracellular matrix
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for MFAP5 blocking peptide

Component of the elastin-associated microfibrils.

NCBI and Uniprot Product Information

• NCBI GI #: 2498553
• NCBI GeneID: 8076
• UniProt Accession #: Q13361; Q7Z490; B0AZL6; D3DUV1
• Molecular Weight: 18,608 Da
• NCBI Official Full Name: Microfibrillar-associated protein 5
• NCBI Official Synonym Full Names: microfibrillar associated protein 5
• NCBI Official Symbol: MFAP5
• NCBI Official Synonym Symbols: AAT9; MP25; MAGP2; MAGP-2; MFAP-5
• NCBI Protein Information: microfibrillar-associated protein 5
• UniProt Protein Name: Microfibrillar-associated protein 5
• Protein Family: Microfibrillar-associated protein
• UniProt Gene Name: MFAP5
• UniProt Synonym Gene Names: MAGP2; MFAP-5; MAGP-2
• UniProt Entry Name: MFAP5_HUMAN

NCBI Description

This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Uniprot Description

MFAP5: Component of the elastin-associated microfibrils. Belongs to the MFAP family.

Protein type: Secreted, signal peptide; Extracellular matrix; Secreted

Chromosomal Location of Human Ortholog: 12p13.1-p12.3

Cellular Component: extracellular region

Molecular Function: extracellular matrix structural constituent

Biological Process: extracellular matrix organization and biogenesis

Disease: Aortic Aneurysm, Familial Thoracic 9