RDH16 blocking peptide

RDH16 Antibody (N-term) Blocking peptide

• Gene Names: RDH16; RODH-4; SDR9C8
• Synonyms: RDH16; RDH16 Antibody (N-term) Blocking peptide; Retinol dehydrogenase 16; 11--; Microsomal NAD(+)-dependent retinol dehydrogenase 4; RoDH-4; Sterol/retinol dehydrogenase; RODH4; RDH16 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 317

• Cellular Location: Microsome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein
• Tissue Location: Highly expressed in adult liver (at protein level). Detected in endometrium, liver and foreskin. Detected in the spineous layers of adult skin, and at lower levels in basal and granular skin layers. Detected in fetal liver and lung
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for RDH16 blocking peptide

Oxidoreductase with a preference for NAD. Oxidizes all- trans-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction.

NCBI and Uniprot Product Information

• NCBI GI #: 150247226
• NCBI GeneID: 8608
• NCBI Accession #: NP_003699.3
• NCBI GenBank Nucleotide #: NM_003708.4
• UniProt Accession #: O75452; Q9UNV2
• Molecular Weight: 35,673 Da
• NCBI Official Full Name: retinol dehydrogenase 16 isoform 1
• NCBI Official Synonym Full Names: retinol dehydrogenase 16 (all-trans)
• NCBI Official Symbol: RDH16
• NCBI Official Synonym Symbols: RODH-4; SDR9C8
• NCBI Protein Information: retinol dehydrogenase 16
• UniProt Protein Name: Retinol dehydrogenase 16
• Protein Family: Retinol dehydrogenase
• UniProt Gene Name: RDH16
• UniProt Synonym Gene Names: RODH4; SDR9C8; RoDH-4
• UniProt Entry Name: RDH16_HUMAN

Uniprot Description

RDH16: Oxidoreductase with a preference for NAD. Oxidizes all- trans-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: Cofactor and Vitamin Metabolism - retinol; Endoplasmic reticulum; Oxidoreductase; Membrane protein, integral; EC 1.1.-.-

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle

Molecular Function: electron carrier activity; retinol dehydrogenase activity

Biological Process: lipid metabolic process