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CALCRL blocking peptide

CALCRL Antibody (Center) Blocking Peptide

Gene Names
CALCRL; CRLR; CGRPR
Synonyms
CALCRL; CALCRL Antibody (Center) Blocking Peptide; Calcitonin gene-related peptide type 1 receptor; CGRP type 1 receptor; Calcitonin receptor-like receptor; CGRPR; CALCRL blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
461
Cellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Location
Predominantly expressed in the lung and heart.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CALCRL blocking peptide
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
52,929 Da
NCBI Official Full Name
Calcitonin gene-related peptide type 1 receptor
NCBI Official Synonym Full Names
calcitonin receptor like receptor
NCBI Official Symbol
CALCRL
NCBI Official Synonym Symbols
CRLR; CGRPR
NCBI Protein Information
calcitonin gene-related peptide type 1 receptor
UniProt Protein Name
Calcitonin gene-related peptide type 1 receptor
UniProt Gene Name
CALCRL
UniProt Synonym Gene Names
CGRPR; CGRP type 1 receptor
UniProt Entry Name
CALRL_HUMAN

Uniprot Description

CALCRL: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q32.1

Cellular Component: endoplasmic reticulum; endosome; integral to plasma membrane; lysosome; plasma membrane

Molecular Function: adrenomedullin receptor activity; G-protein coupled receptor activity; protein binding; protein transporter activity

Biological Process: angiogenesis; calcium ion transport; cAMP biosynthetic process; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of cAMP biosynthetic process; protein transport; receptor internalization

Research Articles on CALCRL

Similar Products

Product Notes

The CALCRL calcrl (Catalog #AAA9222923) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CALCRL, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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