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NACC2 blocking peptide

NACC2 Antibody (C-term) Blocking Peptide

Gene Names
NACC2; RBB; BEND9; NAC-2; BTBD14; BTBD31; BTBD14A
Synonyms
NACC2; NACC2 Antibody (C-term) Blocking Peptide; Nucleus accumbens-associated protein 2; NAC-2; BTB/POZ domain-containing protein 14A; Repressor with BTB domain and BEN domain; BTBD14A; NAC2; RBB; NACC2 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
587
Cellular Location
Nucleus. Note: Predominantly associated with chromatin
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NACC2 blocking peptide
Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
62,837 Da
NCBI Official Full Name
Nucleus accumbens-associated protein 2
NCBI Official Synonym Full Names
NACC family member 2
NCBI Official Symbol
NACC2
NCBI Official Synonym Symbols
RBB; BEND9; NAC-2; BTBD14; BTBD31; BTBD14A
NCBI Protein Information
nucleus accumbens-associated protein 2
UniProt Protein Name
Nucleus accumbens-associated protein 2
UniProt Gene Name
NACC2
UniProt Synonym Gene Names
BTBD14A; NAC2; RBB; NAC-2
UniProt Entry Name
NACC2_HUMAN

Uniprot Description

BTBD14A: Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53. Homooligomer; mediated by the BTB domain. Interacts with the NuRD complex. Interacts (via C-terminal part) with HDAC2. Interacts (via BTB domain) with MTA1, MTA2 and MTA3

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: nuclear body; nuclear chromatin; nucleus; NuRD complex

Molecular Function: histone deacetylase activity; histone deacetylase binding; protein binding; protein homodimerization activity

Biological Process: negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; protein homooligomerization

Research Articles on NACC2

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Product Notes

The NACC2 nacc2 (Catalog #AAA9221943) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NACC2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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