Dapk2 blocking peptide
Mouse Dapk2 Antibody (N-term) Blocking Peptide
Synonyms
Dapk2; Mouse Dapk2 Antibody (N-term) Blocking Peptide; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1; Dapk2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
370
Cellular Location
Cytoplasm. Cytoplasmic vesicle, autophagosome lumen
Tissue Location
Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Dapk2 blocking peptide
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell deaths signal. The former involves caspase activation, chromatin and mitochondrial condensation while the latter involves caspase-independent cell death in conjunction with accumulation of mature autophagic vesicles, plasma membrane blebs, and nuclear condensation without DNA degradation. Mediator of anoikis and a suppressor of beta- catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
56,035 Da
NCBI Official Full Name
Death-associated protein kinase 2
NCBI Official Synonym Full Names
death-associated protein kinase 2
NCBI Official Symbol
Dapk2
NCBI Protein Information
death-associated protein kinase 2
UniProt Protein Name
Death-associated protein kinase 2
Protein Family
UniProt Gene Name
Dapk2
UniProt Synonym Gene Names
DAP kinase 2; DRP-1
UniProt Entry Name
DAPK2_MOUSE
Uniprot Description
DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle.
Protein type: EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; DAPK family
Cellular Component: cytoplasm
Molecular Function: ATP binding; calmodulin binding; identical protein binding
Biological Process: anoikis; protein amino acid phosphorylation
Research Articles on Dapk2
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Product Notes
The Dapk2 dapk2 (Catalog #AAA9221031) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Dapk2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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