PHF17 Blocking Peptide | JADE1 blocking peptide
PHF17 Antibody (N-term) Blocking peptide
Gene Names
JADE1; PHF17
Synonyms
PHF17; PHF17 Antibody (N-term) Blocking peptide; Protein Jade-1; Jade family PHD finger protein 1; PHD finger protein 17; JADE1; KIAA1807; JADE1 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of PHF17. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
842
Cellular Location
Cytoplasm. Nucleus.
Tissue Location
Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for JADE1 blocking peptide
Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
58,370 Da
NCBI Official Full Name
Protein Jade-1
NCBI Official Synonym Full Names
jade family PHD finger 1
NCBI Official Symbol
JADE1
NCBI Official Synonym Symbols
PHF17
NCBI Protein Information
protein Jade-1
UniProt Protein Name
Protein Jade-1
Protein Family
UniProt Gene Name
JADE1
UniProt Synonym Gene Names
KIAA1807; PHF17
UniProt Entry Name
JADE1_HUMAN
Uniprot Description
JADE1: Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Belongs to the JADE family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor
Chromosomal Location of Human Ortholog: 4q26-q27
Cellular Component: cytoplasm; histone acetyltransferase complex; nucleoplasm; nucleus; plasma membrane
Molecular Function: protein binding
Research Articles on JADE1
Similar Products
Product Notes
The JADE1 jade1 (Catalog #AAA9219901) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PHF17, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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