NIP1 (BH3 Domain Specific) Blocking Peptide | BNIP1 blocking peptide
NIP1 Antibody (BH3 Domain Specific) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011]
Uniprot Description
BNIP1: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. Belongs to the SEC20 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 5q33-q34
Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; intracellular membrane-bound organelle; nuclear envelope; SNARE complex
Molecular Function: protein binding; SNAP receptor activity
Biological Process: apoptosis; endoplasmic reticulum membrane fusion; endoplasmic reticulum organization and biogenesis; negative regulation of apoptosis; retrograde vesicle-mediated transport, Golgi to ER
Research Articles on BNIP1
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Product Notes
The BNIP1 bnip1 (Catalog #AAA9219709) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NIP1 (BH3 Domain Specific), Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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