MOGT2 Blocking Peptide | Mogat2 blocking peptide
Mouse MOGT2 Antibody (C-term) Blocking Peptide
Gene Names
Mogat2; MGAT2; Mgat1l; DGAT2L5
Synonyms
MOGT2; Mouse MOGT2 Antibody (C-term) Blocking Peptide; 2-acylglycerol O-acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; MGAT2; Diacylglycerol acyltransferase 2-like protein 5; Monoacylglycerol O-acyltransferase 1-like; Monoacylglycerol O-acyltransferase 2; Mogat2; Dgat2l5; Mgat1l; Mogat2 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human Mouse MOGT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
334
Cellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location
Mainly expressed in small intestine. Detected in the small intestine in a proximal-to-distal gradient that correlated with fat absorption pattern. Present not only in the villi, but also in the crypt regions of the small intestine, which suggests that expression occurs prior to the maturation of enterocytes. Not detectable in other sections of the digestive tract, including stomach, cecum, colon and rectum, or other tissues such as kidney, liver and adipocytes (at protein level) Also detected in kidney, adipose and stomach. Expressed at very low level in liver, skeletal muscle and spleen. Not expressed in brain, heart, lung, skin, testis and thymus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Mogat2 blocking peptide
Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
38,591 Da
NCBI Official Full Name
2-acylglycerol O-acyltransferase 2
NCBI Official Synonym Full Names
monoacylglycerol O-acyltransferase 2
NCBI Official Symbol
Mogat2
NCBI Official Synonym Symbols
MGAT2; Mgat1l; DGAT2L5
NCBI Protein Information
2-acylglycerol O-acyltransferase 2
UniProt Protein Name
2-acylglycerol O-acyltransferase 2
Protein Family
UniProt Gene Name
Mogat2
UniProt Synonym Gene Names
Dgat2l5; Mgat1l; MGAT2
UniProt Entry Name
MOGT2_MOUSE
Uniprot Description
MOGAT2: Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity. Belongs to the diacylglycerol acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Acetyltransferase; Membrane protein, integral; EC 2.3.1.22
Cellular Component: endoplasmic reticulum
Molecular Function: 2-acylglycerol O-acyltransferase activity; acetyltransferase activity
Biological Process: diacylglycerol biosynthetic process; intestinal absorption; lipid metabolic process; monoacylglycerol metabolic process; triacylglycerol biosynthetic process
Research Articles on Mogat2
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Product Notes
The Mogat2 mogat2 (Catalog #AAA9218241) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MOGT2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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