CLEC11A blocking peptide

CLEC11A Antibody (Center) Blocking peptide

• Gene Names: CLEC11A; P47; SCGF; LSLCL; CLECSF3
• Synonyms: CLEC11A; CLEC11A Antibody (Center) Blocking peptide; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; Lymphocyte secreted C-type lectin; Stem cell growth factor; p47; CLECSF3; LSLCL; SCGF; CLEC11A blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 323

• Cellular Location: Cytoplasm. Secreted
• Tissue Location: Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for CLEC11A blocking peptide

Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.

NCBI and Uniprot Product Information

• NCBI GI #: 34223087
• NCBI GeneID: 6320
• UniProt Accession #: Q9Y240; B2RAD4
• Molecular Weight: 35,695 Da
• NCBI Official Full Name: C-type lectin domain family 11 member A
• NCBI Official Synonym Full Names: C-type lectin domain family 11 member A
• NCBI Official Symbol: CLEC11A
• NCBI Official Synonym Symbols: P47; SCGF; LSLCL; CLECSF3
• NCBI Protein Information: C-type lectin domain family 11 member A
• UniProt Protein Name: C-type lectin domain family 11 member A
• Protein Family: C-type lectin domain family
• UniProt Gene Name: CLEC11A
• UniProt Synonym Gene Names: CLECSF3; LSLCL; SCGF
• UniProt Entry Name: CLC11_HUMAN

NCBI Description

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

CLEC11A: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: extracellular region; extracellular space

Molecular Function: growth factor activity

Biological Process: positive regulation of cell proliferation