Western Blot (WB)
(Western blot analysis of HSPB3 expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human HSPB3 Polyclonal Antibody | anti-HSPB3 antibody
HSPB3 Antibody
Western Blot (WB)
(Western blot analysis of HSPB3 expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of HSPB3 expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a muscle-specific small heat shock protein. A mutation in this gene is the cause of autosomal dominant distal hereditary motor neuropathy type 2C.[provided by RefSeq, Sep 2010]
Uniprot Description
HSPB3: Inhibitor of actin polymerization. Defects in HSPB3 are the cause of distal hereditary motor neuronopathy type 2C (HMN2C). It is a neuromuscular disorder. Distal hereditary motor neuronopathies constitute a heterogeneous group of neuromuscular disorders caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal muscles of the lower limbs and/or to the distal upper limbs. Belongs to the small heat shock protein (HSP20) family.
Protein type: Heat shock protein
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: cytoplasm; nucleus
Biological Process: response to unfolded protein
Disease: Neuronopathy, Distal Hereditary Motor, Type Iic
Research Articles on HSPB3
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Product Notes
The HSPB3 hspb3 (Catalog #AAA9418202) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HSPB3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSPB3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the HSPB3 hspb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSPB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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