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Western Blot (WB) (All lanes : Anti-AKR7A3 Antibody (Center) at 1:2000 dilutionLane 1: human liver lysateLane 2: SK-BR-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human AKR7A3 Polyclonal Antibody | anti-AKR7A3 antibody

AKR7A3 Antibody (Center)

Gene Names
AKR7A3; AFAR2
Reactivity
Human
Applications
Western Blot
Synonyms
AKR7A3; Polyclonal Antibody; AKR7A3 Antibody (Center); Purified Rabbit Polyclonal Antibody (Pab); Aflatoxin B1 aldehyde reductase member 3; 1.-.-.-; AFB1 aldehyde reductase 2; AFB1-AR 2; AFAR2; anti-AKR7A3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Sequence Length
331
Applicable Applications for anti-AKR7A3 antibody
Western Blot (WB)
Application Notes
WB~~1:2000
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-AKR7A3 Antibody (Center) at 1:2000 dilutionLane 1: human liver lysateLane 2: SK-BR-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-AKR7A3 Antibody (Center) at 1:2000 dilutionLane 1: human liver lysateLane 2: SK-BR-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-AKR7A3 antibody
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Product Categories/Family for anti-AKR7A3 antibody
References
Knight L.P.,et al.Carcinogenesis 20:1215-1223(1999). Praml C.,et al.Oncogene 22:4765-4773(2003). Gregory S.G.,et al.Nature 441:315-321(2006). Bodreddigari S.,et al.Chem. Res. Toxicol. 21:1134-1142(2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,206 Da
NCBI Official Full Name
aflatoxin B1 aldehyde reductase member 3
NCBI Official Synonym Full Names
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
NCBI Official Symbol
AKR7A3
NCBI Official Synonym Symbols
AFAR2
NCBI Protein Information
aflatoxin B1 aldehyde reductase member 3
UniProt Protein Name
Aflatoxin B1 aldehyde reductase member 3
UniProt Gene Name
AKR7A3
UniProt Synonym Gene Names
AFAR2; AFB1-AR 2
UniProt Entry Name
ARK73_HUMAN

NCBI Description

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

Uniprot Description

AKR7A3: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.

Protein type: EC 1.-.-.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: cytosol

Molecular Function: aldo-keto reductase activity; electron carrier activity; protein binding

Biological Process: aldehyde metabolic process; xenobiotic metabolic process

Research Articles on AKR7A3

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Product Notes

The AKR7A3 akr7a3 (Catalog #AAA9217012) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AKR7A3 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AKR7A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB~~1:2000. Researchers should empirically determine the suitability of the AKR7A3 akr7a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKR7A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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