Western Blot (WB)
(Western blot analysis of BIN3 Antibody (N-term) in HepG2, K562 cell line lysates (35ug/lane). BIN3 (arrow) was detected using the purified Pab.)
Rabbit BIN3 Polyclonal Antibody | anti-BIN3 antibody
BIN3 Antibody (N-term)
Western Blot (WB)
(Western blot analysis of BIN3 Antibody (N-term) in HepG2, K562 cell line lysates (35ug/lane). BIN3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of BIN3 Antibody (N-term) in HepG2, K562 cell line lysates (35ug/lane). BIN3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with BIN3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with BIN3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]
Uniprot Description
BIN3: Involved in cytokinesis and septation where it has a role in the localization of F-actin. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 8p21.3
Cellular Component: cytoplasm; actin filament
Molecular Function: protein binding; cytoskeletal adaptor activity
Biological Process: barrier septum formation; unidimensional cell growth; protein localization; actin filament organization; cytokinesis; skeletal muscle fiber development; myoblast migration involved in skeletal muscle regeneration
Research Articles on BIN3
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Product Notes
The BIN3 bin3 (Catalog #AAA9214792) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The BIN3 Antibody (N-term) reacts with Human (Predicted Reactivity: Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's BIN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the BIN3 bin3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BIN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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