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Western Blot (WB) (POLS Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the POLS antibody detected the POLS protein (arrow).)

Rabbit POLS Polyclonal Antibody | anti-PAPD7 antibody

POLS Antibody (Center)

Gene Names
PAPD7; LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
POLS; Polyclonal Antibody; POLS Antibody (Center); Non-canonical poly(A) RNA polymerase PAPD7; DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal uridylyltransferase 5; TUTase 5; Topoisomerase-related function protein 4-1; TRF4-1; PAPD7; TRF4; anti-PAPD7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This POLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human POLS.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
152-180
Sequence Length
541
Applicable Applications for anti-PAPD7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(POLS Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the POLS antibody detected the POLS protein (arrow).)

Western Blot (WB) (POLS Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the POLS antibody detected the POLS protein (arrow).)
Related Product Information for anti-PAPD7 antibody
The protein encoded by this gene is a DNA polymerase that
is likely involved in DNA repair. In addition, the encoded protein
may be required for sister chromatid adhesion. Alternatively
spliced transcript variants that encode different isoforms have
been described.
References
Jarjanazi, H., et al. Hum. Mutat. 29(4):461-467(2008)
Carson, D.R., et al. Proc. Natl. Acad. Sci. U.S.A. 98(15):8270-8275(2001)
Wang, Z., et al. Science 289(5480):774-779(2000)
Walowsky, C., et al. J. Biol. Chem. 274(11):7302-7308(1999)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
82360
NCBI Official Full Name
non-canonical poly(A) RNA polymerase PAPD7 isoform 2
NCBI Official Synonym Full Names
PAP associated domain containing 7
NCBI Official Symbol
PAPD7
NCBI Official Synonym Symbols
LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5
NCBI Protein Information
non-canonical poly(A) RNA polymerase PAPD7
UniProt Protein Name
Non-canonical poly(A) RNA polymerase PAPD7
UniProt Gene Name
PAPD7
UniProt Synonym Gene Names
POLS; TRF4; TUTase 5; TRF4-1
UniProt Entry Name
PAPD7_HUMAN

NCBI Description

The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

POLS: DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family.

Protein type: DNA replication; EC 2.7.7.19; DNA repair, damage; Transferase

Chromosomal Location of Human Ortholog: 5p15

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: polynucleotide adenylyltransferase activity; DNA binding; SMC protein binding; metal ion binding; DNA-directed DNA polymerase activity

Biological Process: response to drug; mitotic chromosome condensation; cell division; double-strand break repair; sister chromatid cohesion

Research Articles on PAPD7

Similar Products

Product Notes

The PAPD7 papd7 (Catalog #AAA9212976) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 152-180. The POLS Antibody (Center) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's POLS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PAPD7 papd7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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