Western Blot (WB)
(Western blot analysis of lysates from Hela, Jurkat cell line (from left to right), using FRG1 Antibody (C-term). MBS9211297 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Rabbit FRG1 Polyclonal Antibody | anti-FRG1 antibody
FRG1 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from Hela, Jurkat cell line (from left to right), using FRG1 Antibody (C-term). MBS9211297 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from Hela, Jurkat cell line (from left to right), using FRG1 Antibody (C-term). MBS9211297 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
repeat units on chromosome 4q35 which are deleted in
facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily
conserved and has related sequences on multiple human chromosomes
but DNA sequence analysis did not reveal any homology to known
genes. In vivo studies demonstrate the encoded protein is localized
to the nucleolus.
Bodega, B., et al. BMC Biol. 7, 41 (2009) :
Pirozhkova, I., et al. PLoS ONE 3 (10), E3389 (2008) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Gabellini, D., et al. Nature 439(7079):973-977(2006)
NCBI and Uniprot Product Information
NCBI Description
This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008]
Uniprot Description
FRG1: May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits. May be involved in pre- mRNA splicing. Belongs to the FRG1 family.
Protein type: RNA splicing; Nucleolus; Spliceosome
Chromosomal Location of Human Ortholog: 4q35
Cellular Component: Cajal body; nucleolus; Z disc
Molecular Function: protein binding; actin binding
Biological Process: nuclear mRNA splicing, via spliceosome; muscle development; rRNA processing
Disease: Facioscapulohumeral Muscular Dystrophy 1
Research Articles on FRG1
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Product Notes
The FRG1 frg1 (Catalog #AAA9211297) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 230-256. The FRG1 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's FRG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FRG1 frg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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