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Western Blot (WB) (Western blot analysis of DOM3Z antibody (N-term Y88) in MCF-7 cell line lysates (35ug/lane). DOM3Z (arrow) was detected using the purified Pab.)

Rabbit DOM3Z Polyclonal Antibody | anti-DXO antibody

DOM3Z Antibody (N-term Y88)

Gene Names
DXO; NG6; RAI1; DOM3L; DOM3Z
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
Western Blot, ELISA, Flow Cytometry, Functional Assay
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DOM3Z; Polyclonal Antibody; DOM3Z Antibody (N-term Y88); Decapping and exoribonuclease protein; DXO; 3113-; 361-; Dom-3 homolog Z; DOM3L; NG6; anti-DXO antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DOM3Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-99 amino acids from the N-terminal region of human DOM3Z.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
73-99
Sequence Length
396
Applicable Applications for anti-DXO antibody
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of DOM3Z antibody (N-term Y88) in MCF-7 cell line lysates (35ug/lane). DOM3Z (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of DOM3Z antibody (N-term Y88) in MCF-7 cell line lysates (35ug/lane). DOM3Z (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of MDA-231 cells using DOM3Z Antibody (N-term Y88)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of MDA-231 cells using DOM3Z Antibody (N-term Y88)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Western Blot (WB)

(Western blot analysis of DOM3Z (arrow) using rabbit polyclonal DOM3Z Antibody (N-term Y88). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DOM3Z gene.)

Western Blot (WB) (Western blot analysis of DOM3Z (arrow) using rabbit polyclonal DOM3Z Antibody (N-term Y88). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DOM3Z gene.)
Related Product Information for anti-DXO antibody
The function of DOM3Z is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that its gene may be a housekeeping gene.
Product Categories/Family for anti-DXO antibody
References
Lehner,B., Genome Res. 14 (7), 1315-1323 (2004)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44929
NCBI Official Full Name
decapping and exoribonuclease protein
NCBI Official Synonym Full Names
decapping exoribonuclease
NCBI Official Symbol
DXO
NCBI Official Synonym Symbols
NG6; RAI1; DOM3L; DOM3Z
NCBI Protein Information
decapping and exoribonuclease protein
UniProt Protein Name
Decapping and exoribonuclease protein
UniProt Gene Name
DXO
UniProt Synonym Gene Names
DOM3L; DOM3Z; NG6; DXO
UniProt Entry Name
DXO_HUMAN

NCBI Description

This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008]

Uniprot Description

DOM3Z: May possess pyrophosphohydrolase activity towards 5' triphosphorylated RNA. Belongs to the Dom3Z family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleoplasm; cytoplasm; plasma membrane

Molecular Function: mRNA binding; 5'-3' exonuclease activity; nucleotide binding; magnesium ion binding

Biological Process: metabolic process; mRNA catabolic process; RNA destabilization

Research Articles on DXO

Similar Products

Product Notes

The DXO dxo (Catalog #AAA9203847) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 73-99. The DOM3Z Antibody (N-term Y88) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's DOM3Z can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the DXO dxo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOM3Z, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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