Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048041 at dilution of 1:100)
Rabbit anti-Human DXO Polyclonal Antibody | anti-DXO antibody
DXO Antibody
Gene Names
DXO; NG6; RAI1; DOM3L; DOM3Z
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
DXO; Polyclonal Antibody; DXO Antibody; Decapping and exoribonuclease protein; Dom-3 homolog Z; DOM3L; DOM3Z; NG6; anti-DXO antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
396
Applicable Applications for anti-DXO antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant Human Decapping and exoribonuclease protein protein (69-266AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161032 / sc-161033 / sc-161034
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048041 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048041 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7048041 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7048041 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-DXO antibody
Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,929 Da
NCBI Official Full Name
decapping and exoribonuclease protein
NCBI Official Synonym Full Names
decapping exoribonuclease
NCBI Official Symbol
DXO
NCBI Official Synonym Symbols
NG6; RAI1; DOM3L; DOM3Z
NCBI Protein Information
decapping and exoribonuclease protein
UniProt Protein Name
Decapping and exoribonuclease protein
Protein Family
UniProt Gene Name
DXO
UniProt Synonym Gene Names
DOM3L; DOM3Z; NG6; DXO
UniProt Entry Name
DXO_HUMAN
NCBI Description
This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DOM3Z: May possess pyrophosphohydrolase activity towards 5' triphosphorylated RNA. Belongs to the Dom3Z family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: cytoplasm; nucleus; plasma membrane
Molecular Function: 5'-3' exonuclease activity; magnesium ion binding; mRNA binding
Biological Process: metabolic process; mRNA catabolic process; RNA destabilization
Research Articles on DXO
Similar Products
Product Notes
The DXO dxo (Catalog #AAA7048041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DXO Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DXO can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the DXO dxo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DXO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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