Western Blot (WB)
(Western blot analysis of extracts from 293 cells, treated with Paclitaxel (1uMl, 24hours), using Telomeric Repeat Binding Factor 1 (Ab-219) antibody.)
anti-Human, Mouse Telomeric Repeat Binding Factor 1 Antibody | anti-TRF antibody
Telomeric Repeat Binding Factor 1 (Ab-219) Antibody
ELISA: 1:5000
Western Blot (WB)
(Western blot analysis of extracts from 293 cells, treated with Paclitaxel (1uMl, 24hours), using Telomeric Repeat Binding Factor 1 (Ab-219) antibody.)
Western Blot (WB)
(Western blot analysis of extracts from 293 cells, treated with Paclitaxel (1uMl, 24hours), using Telomeric Repeat Binding Factor 1 (Ab-219) antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]
Uniprot Description
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Research Articles on TRF
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Product Notes
The TRF terf1 (Catalog #AAA858920) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Telomeric Repeat Binding Factor 1 (Ab-219) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Telomeric Repeat Binding Factor 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the TRF terf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Telomeric Repeat Binding Factor 1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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