Testing Data
anti-Human Cytochrome P450 11B1/2 Antibody | anti-CYPXIB1 antibody
Cytochrome P450 11B1/2 Antibody
Gene Names
CYP11B1; FHI; CPN1; CYP11B; P450C11
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Cytochrome P450 11B1/2; Cytochrome P450 11B1/2 Antibody; C11B1; CPN1; CYP11B; CYP11B1; Cytochrome P-450c11; Cytochrome P450 11B1; mitochondrial; cytochrome p450 XIB1; cytochrome P450; family 11; subfamily B; polypeptide 1; subfamily XIB (steroid 11-beta-hydroxylase); Cytochrome P450C11; DKFZp686B05283; FHI; FLJ36771; P450C11; S11BH; Steroid 11-beta-hydroxylase; steroid 11-beta-monooxygenase; anti-CYPXIB1 antibody
Reactivity
Human
Specificity
Cytochrome P450 11B1/2 antibody detects endogenous levels of total Cytochrome P450 11B1/2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
503
Applicable Applications for anti-CYPXIB1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:40000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human Cytochrome P450 11B1/2.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
Testing Data
Product Categories/Family for anti-CYPXIB1 antibody
References
Mornet E., J. Biol. Chem. 264:20961-20967(1989). Kawamoto T., FEBS Lett. 269:345-349(1990). Nusbaum C., Nature 439:331-335(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,750 Da
NCBI Official Full Name
cytochrome P450 11B1, mitochondrial isoform 1
NCBI Official Synonym Full Names
cytochrome P450 family 11 subfamily B member 1
NCBI Official Symbol
CYP11B1
NCBI Official Synonym Symbols
FHI; CPN1; CYP11B; P450C11
NCBI Protein Information
cytochrome P450 11B1, mitochondrial
UniProt Protein Name
Cytochrome P450 11B1, mitochondrial
UniProt Gene Name
CYP11B1
UniProt Synonym Gene Names
S11BH; Cytochrome P450C11
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Research Articles on CYPXIB1
Similar Products
Product Notes
The CYPXIB1 cyp11b1 (Catalog #AAA858322) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 11B1/2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 11B1/2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:40000. Researchers should empirically determine the suitability of the CYPXIB1 cyp11b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 11B1/2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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