anti-Human ARHGDIG Antibody | anti-ARHGDIG antibody

ARHGDIG Antibody

Cat. Num. AAA858194

• Gene Names: ARHGDIG; RHOGDI-3
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: ARHGDIG; ARHGDIG Antibody; GDIR3; Rho GDI 3; Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP-dissociation inhibitor 3; Rho-GDI gamma; RhoGDI gamma; RHOGDI-3; anti-ARHGDIG antibody

• Reactivity: Human
• Specificity: ARHGDIG antibody detects endogenous levels of total ARHGDIG protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 225

• Applicable Applications for anti-ARHGDIG antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:1000; ELISA: 1:10000
• Immunogen: The antiserum was produced against synthesized peptide derived from Internal of human ARHGDIG.
• Preparation and Storage: Store at-20 degree C for 1 year.

Testing Data

Product Categories/Family for anti-ARHGDIG antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Adra C.N., Proc. Natl. Acad. Sci. U.S.A. 94:4279-4284(1997). Adra C.N., Genomics 53:104-109(1998). Hayashi A., Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

• NCBI GI #: 83313661
• NCBI GeneID: 398
• NCBI Accession #: NP_001167.2
• NCBI GenBank Nucleotide #: NM_001176.3
• UniProt Accession #: Q99819; Q4TT69; Q96S29
• Molecular Weight: 25,098 Da
• NCBI Official Full Name: rho GDP-dissociation inhibitor 3
• NCBI Official Synonym Full Names: Rho GDP dissociation inhibitor gamma
• NCBI Official Symbol: ARHGDIG
• NCBI Official Synonym Symbols: RHOGDI-3
• NCBI Protein Information: rho GDP-dissociation inhibitor 3
• UniProt Protein Name: Rho GDP-dissociation inhibitor 3
• Protein Family: Rho GDP-dissociation inhibitor
• UniProt Gene Name: ARHGDIG
• UniProt Synonym Gene Names: Rho GDI 3

NCBI Description

The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010]

Uniprot Description

Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.