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Rabbit ALDH1L1 Monoclonal Antibody | anti-ALDH1L1 antibody

ALDH1L1

Gene Names
ALDH1L1; FDH; FTHFD; 10-fTHF; 10-FTHFDH
Reactivity
Human, Mouse, Rat
Purity
Protein A Affinity Purified
Synonyms
ALDH1L1; Monoclonal Antibody; Cytosolic 10-formyltetrahydrofolate dehydrogenase; Aldehyde dehydrogenase family 1 member L1; 10-FTHFDH; FDH; FTHFD; anti-ALDH1L1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
JU53-54
Purity/Purification
Protein A Affinity Purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. 0.05% Sodium Azide.
Sequence Length
902
Immunogen
Recombinant protein within human ALDH1L1 aa 50-300
Antibody Type
Recombinant Rabbit Monoclonal Antibody
Preparation and Storage
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member L1
NCBI Official Symbol
ALDH1L1
NCBI Official Synonym Symbols
FDH; FTHFD; 10-fTHF; 10-FTHFDH
NCBI Protein Information
cytosolic 10-formyltetrahydrofolate dehydrogenase
UniProt Protein Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
UniProt Gene Name
ALDH1L1
UniProt Synonym Gene Names
FTHFD; 10-FTHFDH; FDH
UniProt Entry Name
AL1L1_HUMAN

NCBI Description

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Uniprot Description

ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Cofactor and Vitamin Metabolism - one carbon pool by folate; Oxidoreductase; EC 1.5.1.6

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: mitochondrion

Molecular Function: methyltransferase activity; aldehyde dehydrogenase (NAD) activity; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; catalytic activity

Biological Process: methylation; biosynthetic process; one-carbon compound metabolic process; 10-formyltetrahydrofolate catabolic process

Research Articles on ALDH1L1

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Product Notes

The ALDH1L1 aldh1l1 (Catalog #AAA8565700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH1L1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "ALDH1L1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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