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Rabbit IDH3G Polyclonal Antibody | anti-IDH3G antibody

IDH3G

Gene Names
IDH3G; H-IDHG
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
IDH3G; Polyclonal Antibody; H-IDHG; anti-IDH3G antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1343
Applicable Applications for anti-IDH3G antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 46-249aa of human IDH3G.
Cellular Localization
Mitochondrion, Nucleolus, Nucleoplasm
Related Product Information for anti-IDH3G antibody
Homo sapiens isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G), transcript variant 1, mRNA
References
Bzymek KP, Colman RF. Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase. Biochemistry. 46(18):5391-7 (2007)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
41KD
NCBI Official Full Name
Homo sapiens isocitrate dehydrogenase 3 (NAD+) gamma, mRNA
NCBI Official Synonym Full Names
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
NCBI Official Symbol
IDH3G
NCBI Official Synonym Symbols
H-IDHG
NCBI Protein Information
isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
Protein Family

NCBI Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008]

Research Articles on IDH3G

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Product Notes

The IDH3G (Catalog #AAA8561521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IDH3G reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IDH3G can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the IDH3G for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IDH3G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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