TBX2 Antibody | anti-TBX2 antibody

TBX2 Antibody

Cat. Num. AAA8513249

• Synonyms: TBX2; TBX2 Antibody; anti-TBX2 antibody

• Sequence Length: 712

Western Blot (WB)

(Western blot analysis TBX2 using HeLa whole cell lysates)

NCBI and Uniprot Product Information

• NCBI GI #: 197333868
• NCBI GeneID: 6909
• NCBI Accession #: NP_005985.3
• NCBI GenBank Nucleotide #: NM_005994.3
• UniProt Accession #: Q13207; Q16424; Q7Z647
• Molecular Weight: 75,066 Da
• NCBI Official Full Name: T-box transcription factor TBX2
• NCBI Official Synonym Full Names: T-box 2
• NCBI Official Symbol: TBX2
• NCBI Protein Information: T-box transcription factor TBX2
• UniProt Protein Name: T-box transcription factor TBX2
• Protein Family: T-box transcription factor
• UniProt Gene Name: TBX2
• UniProt Synonym Gene Names: T-box protein 2

NCBI Description

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. May be required for cardiac atrioventricular canal formation.