SDS-Page
LILRB4/CD85k/ILT3, Cynomolgus Active Protein | LILRB4 active protein
Human CellExp LILRB4/CD85k/ILT3, Cynomolgus Recombinant
Purity
>85% by SDS-PAGE
Synonyms
LILRB4/CD85k/ILT3; Cynomolgus; Human CellExp LILRB4/CD85k/ILT3; Cynomolgus Recombinant; LILRB4; ILT3; LIR5; CD85K; HM18; LILRB4 active protein
Host
HEK293 cells
Purity/Purification
>85% by SDS-PAGE
Form/Format
Lyophilized from 0.22 um filtered solution in PBS pH7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Gene Source
Human
Endotoxin
<1.0 EU per/ug
Biological Activity
Immobilized Human ANGPTL7, His Tag at 5 ug/mL (100 uL/well) can bind Cynomolgus LILRB4, Fc Tag with a linear range of 10-156 ng/mL.
Measured by its binding ability in a functional ELISA.
Measured by its binding ability in a functional ELISA.
Reconstitution Instruction
Reconstitute in sterile deionized water to the desired protein concentration.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for LILRB4 active protein
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4/CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4/CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. Receptor for class I MHC antigens
Product Categories/Family for LILRB4 active protein
NCBI and Uniprot Product Information
NCBI GeneID
Molecular Weight
52.7kDa
Protein Family
Similar Products
Product Notes
The LILRB4 (Catalog #AAA849814) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LILRB4/CD85k/ILT3, Cynomolgus, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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