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Structure

Resminostat Biochemical

Resminostat (hydrochloride)

Purity
>=98% by HPLC
Synonyms
Resminostat; Resminostat (hydrochloride); 3-[1-[[4-[ (dimethylamino) methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-2-propenamide; monohydrochloride; 4SC-201 hydrochloride; RAS2410 hydrochloride; (E)-3-[1- (4-dimethylaminomethyl-benzenesulfonyl)-1H-pyrrol-3-yl]-N-hydroxy-acrylamide hydrochloride; Resminostat biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by HPLC
Form/Format
Crystalline solid
Solubility
~0.5 mg/ml in PBS
pH 7.2
~10 mg/ml in DMSO
~0.5 mg/ml in DMF
Molecular Formula
C??H??ClN?O?S
CAS Number
1187075-34-8
PubChem CID
16662815
SMILES
CN (C)CC1=CC=C (C=C1)S (=O)(=O)N2C=CC (=C2)C=CC (=O)NO.Cl
InChi
InChI=1S/C16H19N3O4S.ClH/c1-18 (2)11-13-3-6-15 (7-4-13)24 (22,23)19-10-9-14 (12-19)5-8-16 (20)17-21;/h3-10,12,21H,11H2,1-2H3, (H,17,20);1H/b8-5+;
InChi Key
BVXPKDRKHXARHY-HAAWTFQLSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months

Structure

Structure
Related Product Information for Resminostat biochemical
Resminostat is a potent inhibitor of histone deacetylases (HDAC) 1, 3 and 6 with IC50 ranging from 43-72 nM. It induces hyperacetylation of histone H4, abrogates cell growth and induces apoptosis in multiple myeloma cells with an IC50 of 2.5-3 uM. It inhibits cell proliferation, induces G0/G1 cell cycle arrest, decreases levels of cyclin D1, cdc25a, Cdk4 and pRb and upregulates p21.
References
https://pubchem.ncbi.nlm.nih.gov/compound/16662815

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Product Notes

The Resminostat (Catalog #AAA848987) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Resminostat, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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