Testing Data
Exodus-2 Active Protein | CCL21 active protein
Exodus-2, Mouse Recombinant
Gene Names
Gm1987; 100038965
Applications
SDS-Page
Purity
>=98%
Synonyms
Exodus-2; Mouse Recombinant; C-C motif chemokine 21; 6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21; CCL21 active protein
Host
E Coli
Purity/Purification
>=98%
Form/Format
Lyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Appearance: Lyophilized powder
Appearance: Lyophilized powder
Sequence
SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Sequence Length
133
Applicable Applications for CCL21 active protein
SDS-PAGE; HPLC
Solubility/Reconstitution Instructions
Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Endotoxin Level
<= 1 EU/mug protein
Biological Activity
The activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
Results
200 ng/mL- 600 ng/mL.
Handling
Centrifuge the vial prior to opening.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for CCL21 active protein
Background: Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
Product Categories/Family for CCL21 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12 kDa
NCBI Official Full Name
predicted gene 1987
NCBI Official Synonym Full Names
predicted gene 1987
NCBI Official Symbol
Gm1987
NCBI Official Synonym Symbols
100038965
NCBI Protein Information
predicted gene 1987
UniProt Protein Name
C-C motif chemokine 21a
Protein Family
UniProt Gene Name
Ccl21a
UniProt Synonym Gene Names
Scya21; Scya21a; TCA4
UniProt Entry Name
CC21A_MOUSE
Uniprot Description
CCL21a: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T- cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Mice carrying an autosomal recessive mutation designated paucity of lymph node T-cells (plt) show dramatically reduced numbers of T-cells in lymph nodes, Peyer patches, and the white pulp of the spleen. Plt seems to correspond to Scya21b. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine
Molecular Function: chemokine receptor binding; chemokine activity
Biological Process: lymph node development; induction of positive chemotaxis
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Product Notes
The CCL21 ccl21a (Catalog #AAA844787) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Exodus-2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE; HPLC. Researchers should empirically determine the suitability of the CCL21 ccl21a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG. It is sometimes possible for the material contained within the vial of "Exodus-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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