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Testing Data

Rabbit anti-Human LDHAL6B Polyclonal Antibody | anti-LDHAL6B antibody

LDHAL6B Antibody (NT)

Gene Names
LDHAL6B; LDHL; LDH6B; LDHAL6
Reactivity
Human
Applications
Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
LDHAL6B; Polyclonal Antibody; LDHAL6B Antibody (NT); LDHAL6; LDHL; L-lactate dehydrogenase A-like 6B; anti-LDHAL6B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
100 ul of antibody in PBS with 0.09% (W/V) sodium azide
Appearance: Colorless liquid
Sequence Length
381
Applicable Applications for anti-LDHAL6B antibody
Western Blot (WB)
Application Notes
Western blot: ~1:1000.
Immunogen
This LDHAL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-71 amino acids from the N-terminal region of human LDHAL6B.
Positive Control
Western blot: K562 cell line lysates
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-LDHAL6B antibody
Polyclonal Antibody to detect LDHAL6B in human samples

Background: L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,943 Da
NCBI Official Full Name
L-lactate dehydrogenase A-like 6B
NCBI Official Synonym Full Names
lactate dehydrogenase A-like 6B
NCBI Official Symbol
LDHAL6B
NCBI Official Synonym Symbols
LDHL; LDH6B; LDHAL6
NCBI Protein Information
L-lactate dehydrogenase A-like 6B
UniProt Protein Name
L-lactate dehydrogenase A-like 6B
Protein Family
UniProt Gene Name
LDHAL6B
UniProt Synonym Gene Names
LDHAL6; LDHL
UniProt Entry Name
LDH6B_HUMAN

Uniprot Description

LDHAL6B: Belongs to the LDH/MDH superfamily. LDH family.

Protein type: Oxidoreductase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; EC 1.1.1.27; Amino Acid Metabolism - cysteine and methionine

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; L-lactate dehydrogenase activity

Biological Process: cellular carbohydrate metabolic process

Research Articles on LDHAL6B

Similar Products

Product Notes

The LDHAL6B ldhal6b (Catalog #AAA841252) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LDHAL6B Antibody (NT) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LDHAL6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot: ~1:1000. Researchers should empirically determine the suitability of the LDHAL6B ldhal6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LDHAL6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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