Insulin Like Growth Factor Binding Protein 3 Recombinant Protein | IGFBP3 recombinant protein

Recombinant Insulin Like Growth Factor Binding Protein 3 (IGFBP3)

Cat. Num. AAA2033599

• Gene Names: IGFBP3; IGFBP-3
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Insulin Like Growth Factor Binding Protein 3; Recombinant Insulin Like Growth Factor Binding Protein 3 (IGFBP3); BP53; IBP3; Growth Hormone-Dependent Binding Protein; Acid Stable Subunit Of The 140 K IGF Complex; IGFBP3 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: S ESEEDRSVDS MENQALPSTH RVPDSKLHSV HTKMDVIKKG HAKDSQRYKV DYESQSTDTQ NFSSESKRET EYGPCRREME DTLNHLKFLN MLSPRGIHIP NCDKKGFYKKKQCRPSKGRK RGFCWCVDKY G
• Sequence Length: 291

• Applicable Applications for IGFBP3 recombinant protein: SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
• Predicted Molecular Mass: 19.1kDa
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Fragment: Ser140~Gly271
• Organism Species: Porcine
• Tag: two N-terminal Tags, His-tag and T7-tag
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 27807007
• NCBI GeneID: 282261
• NCBI Accession #: NP_776981.1
• NCBI GenBank Nucleotide #: NM_174556.1
• Molecular Weight: 31,570 Da
• NCBI Official Full Name: insulin-like growth factor-binding protein 3
• NCBI Official Symbol: IGFBP3
• NCBI Official Synonym Symbols: IGFBP-3
• NCBI Protein Information: insulin-like growth factor-binding protein 3
• UniProt Protein Name: Insulin-like growth factor-binding protein 3
• Protein Family: Insulin-like growth factor-binding protein
• UniProt Gene Name: IGFBP3
• UniProt Synonym Gene Names: IBP-3; IGF-binding protein 3; IGFBP-3
• UniProt Entry Name: IBP3_BOVIN

Uniprot Description

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.