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Structure

BT2 biochemical

BT2 (BCKDC Kinase Inhibitor)

Purity
>=98% by HPLC
Synonyms
BT2; BT2 (BCKDC Kinase Inhibitor); 3; 6-Dichlorobenzo[b]thiophene-2-carboxylic acid; BT2 biochemical
Ordering
For Research Use Only!
Specificity
A BCKDC kinase inhibitor
Purity/Purification
>=98% by HPLC
Form/Format
Off-white solid
Solubilities
~20mg/ml DMSO
Molecular Formula
C?H?Cl?O?S
InChi
InChI=1S/C9H4Cl2O2S/c10-4-1-2-5-6(3-4)14-8(7(5)11)9(12)13/h1-3H; (H; 12; 13)
InChi Key
AAHPIJMQJAZYTM-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1Cl)SC(=C2Cl)C(=O)O
CAS Number
34576-94-8
PubChem CID
739884
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36months
Country of Origin: USA

Structure

Structure
Related Product Information for BT2 biochemical
BT2 is an inhibitor of the mitochondrial branched-chain a-ketoacid dehydrogenase complex kinase (BCKDC)-IC50 = 3.19uM. Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 also acts as a moderate inhibitor (Ki = 59uM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.
References
https://pubchem.ncbi.nlm.nih.gov/compound/739884

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Product Notes

The BT2 (Catalog #AAA8400403) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BT2, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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