Immunohistochemistry (IHC)
Rabbit anti-Human p21 Monoclonal Antibody | anti-p21 antibody
Anti-p21 (KO Validated) Antibody
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Affinity purified
Synonyms
p21; Monoclonal Antibody; Anti-p21 (KO Validated) Antibody; CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1; CDKN1A; anti-p21 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Specificity
Rabbit monoclonal knockout validated antibody to detect the expression of p21 in human samples
Purity/Purification
Affinity purified
Form/Format
Colorless liquid. In PBS with 0.02% sodium azide; 50% glycerol; pH7.3
Applicable Applications for anti-p21 antibody
Immunohistochemistry (IHC); Western Blotting (WB)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Antibody Target
p21
Immunogen
Synthetic peptide derived from human p21
Preparation and Storage
Store at -20 degree C. The antibody solution should be gently mixed before use.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-p21 antibody
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.
Product Categories/Family for anti-p21 antibody
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Product Notes
The p21 (Catalog #AAA8400202) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-p21 (KO Validated) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p21 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC); Western Blotting (WB). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the p21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p21, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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