Flow Cytometry (FC/FACS)
(Staining of platelets with 0.5 ug of Mouse IgG1 Isotype Control (open histogram) or 0.5 ug of CD51 antibody/CD61 (Integrin alpha/beta) Purified followed by Anti-Mouse IgG (FITC) (filled histogram).)
Mouse CD51/61 Monoclonal Antibody | anti-CD51/61 antibody
CD51/61 antibody
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Functional Assay, Immunoprecipitation
Purity
CD51/61 antibody was purified by affinity chromatography.
Synonyms
CD51/61; Monoclonal Antibody; CD51/61 antibody; Monoclonal CD51/61; Anti-CD51/61; CD61/CD51; CD51-61; CD51; vitronectin Receptor; CD51 + CD61; Integrin av b3; CD61; CD51 and CD61; anti-CD51/61 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
23C6
Specificity
Human
Purity/Purification
CD51/61 antibody was purified by affinity chromatography.
Form/Format
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration
500 ug/ml (varies by lot)
Applicable Applications for anti-CD51/61 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Functional Assay, Immunoprecipitation (IP)
Application Notes
FC: <= 0.5 ug/test
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest.
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest.
Biological Significance
The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ~120 kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1, beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.
Preparation and Storage
Store at 2-8 degree C. Do not freeze. Protect from light.
Flow Cytometry (FC/FACS)
(Staining of platelets with 0.5 ug of Mouse IgG1 Isotype Control (open histogram) or 0.5 ug of CD51 antibody/CD61 (Integrin alpha/beta) Purified followed by Anti-Mouse IgG (FITC) (filled histogram).)
Flow Cytometry (FC/FACS)
(Staining of platelets with 0.5 ug of Mouse IgG1 Isotype Control (open histogram) or 0.5 ug of CD51 antibody/CD61 (Integrin alpha/beta) Purified followed by Anti-Mouse IgG (FITC) (filled histogram).)
Related Product Information for anti-CD51/61 antibody
Mouse monoclonal CD51/61 antibody
Product Categories/Family for anti-CD51/61 antibody
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Product Notes
The CD51/61 (Catalog #AAA838525) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD51/61 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Functional Assay, Immunoprecipitation (IP). FC: <= 0.5 ug/test A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest. Researchers should empirically determine the suitability of the CD51/61 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD51/61, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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